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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MDM2 bound to LATS2 inhibits TP53. 2 / 2

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reach

"Active LATS2 binds and inhibits the E3 ubiquitin ligase MDM2, which targets p53 for destruction, thereby indirectly leading to the stabilization of p53."

25126788

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reach

"Active LATS2 also binds to and inhibits the E3 ubiquitin ligase MDM2, which normally targets p53 for destruction."

25126788

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...