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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

GSK3B decreases the amount of IRS1. 1 / 1

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"Further support for the hypothesis that reduced GSK-3beta activity in beta-Gsk-3beta -/- mice can increase IRS1 and IRS2 levels and insulin signalling was obtained by in vitro experiments with a potent and selective inhibitor of GSK-3 activity, SB216763 [XREF_BIBR]."

20821187

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...