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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TNFAIP3 binds TNFAIP3 and TNIP1. 2 / 2

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"The TNFAIP3 interacting protein 1, (TNIP1), also known as ABIN1, interacts with TNFAIP3 and A20 and promotes inhibition of NF-kappaB activity [XREF_BIBR, XREF_BIBR]."

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"Genetic studies have shown an association between multiple autoimmune diseases and TNFAIP3 (A20) and TNIP1 (ABIN1), both repressors of NF-kappaB and of IKBKE (IKKepsilon), which is an NF-kappaB activator."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...