IndraLab

Statements


MYC bound to MAX activates cell cycle. 2 / 2
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"Blocking c-MYC and MAX heterodimerization with the small-molecule inhibitor 10058-F4 significantly inhibits ovarian cancer cell proliferation in part by inducing apoptosis and cell cycle arrest."

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"The MYC and MAX heterodimer can also support continued cell cycle progression through the repression of multiple CKIs, including p15, p18, p21, and p27 [XREF_BIBR]."