IndraLab

Statements


CTNNB1 bound to KLF4 inhibits CTNNB1. 2 / 2
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"In addition, we suggest the existence of a dual mechanism whereby 5-ASA-mediated beta-catenin inhibition is caused by mu-protocadherin-dependent sequestration of beta-catenin to the plasma membrane and by the direct binding of KLF4 to beta-catenin."

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"31 Similarly, KLF4 is expressed in the villi, and the interaction of KLF4 and beta-catenin inhibits beta-catenin transcriptional activity and regulates intestinal homeostasis."