IndraLab

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CYLD-R324A inhibits ROCK. 1 / 1
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"Because microtubule disruption has been linked to release of at least two Rho GEFs, Trio and RhoGEF-H1, which subsequently activate ROCK, we sought to test whether the non cleavable R324A CYLD mutant can also suppress ROCK kinase activity following thrombin treatment."