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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SHC1 binds EGFR, GRB2, and Sos. 1 / 1

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"Stimulation of EDNRB in Müller cells resulted in phosphorylation of tyrosine residue 1173 of the EGFR, which is one of the major autophosphorylation site that allows binding of GRB2, SOS and SHC adapter proteins to EGFR and that mediates Ras-Raf activated MAPK/ERK signaling [ xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...