Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MiR-497 decreases the amount of IRS1. 2 / 2

| 2

➶

reach

"Total proteins from representative tumor samples were analyzed by western blotting, and the results demonstrated that miR-497 suppressed the expression of IRS1 and p-AKT, as well as p-ERK1/2, in vivo (XREF_FIG)."

29163678

➶

reach

"However, in the mutant group, no detectable change in luciferase activity was observed (XREF_FIG), suggesting that miR-497 suppressed the transcription of the IRS1 gene by targeting the putative 3 ' UTR of IRS1 mRNA independently."

29163678

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...