IndraLab

Statements


Phosphorylated AKT activates phosphorylated MTOR. 4 / 4
| 1 3

reach
"Pharmacological inhibition of p-Akt with SH-6 inhibited not only p-Akt but also p-mTOR."

reach
"PI-3K was increased up to twofold relative to the naive control (2.35 +/-0.5 vs. 1.00 +/-0.01 of control, p < 0.01) and both p-Akt and p-mTOR were increased nearly three times (p-Akt 2.4 +/-0.63 vs. 1.00 +/-0.02 of control, p < 0.01, and p-mTOR 2.18 +/-0.22 vs. 1.00 +/-0.02 of control, p < 0.01)."

reach
"Overall, our results showed that p-Akt and p-AMPK antagonistically targeted p-mTOR to regulate mitochondrial translation proteins to affect autophagy and apoptosis."

eidos
"Finally , the results showed that YQFM could activate the PI 3 K / AKT / mTOR pathway by enhancing the p-AKT , p-PI 3 K and p-mTOR expressions ."