IndraLab

Statements

COPS5 activates cell growth. 9 / 11
| 2 7
reach
"XREF_BIBR used T83 (a new 4-arylidene curcumin analogue) to inhibit the expression of Jab1 in NPC cells, demonstrating that inhibition of Jab1 could reduce tumor cell growth, induce G 2 / M arrest, and increase tumor cell apoptosis, thus enhancing the sensitivities of NPC cells to radiotherapy."
25859408
reach
"In HCC, abnormal expression of JAB1 can significantly reduce CDKN1C and p57 levels and promote tumor cell growth."
33486902
eidos
"JAB1 promoted ESCC cell growth The CCK-8 assay revealed that the Eca109 and EC9706 cells transfected with the JAB1 overexpression lentivirus showed significantly increased absorbance compared to normal cells , ( Fig 3a ) ."
32064781
reach
"Experiments showing that the knock-down of p8 expression results in a strong inhibition of Jab1 activity confirmed that the mechanism by which Jab1 promotes cell growth by decreasing p27 level is p8 dependent."
16300740
eidos
"Similar to AR-positive PC cells , inhibition of CSN5 repressed cell growth ( Fig. 4A ) ."
34802033
reach
"Our group recently found that Jab1 contributes to NPC tumorigenesis and resistance to radiotherapy by promoting NPC cell growth, dysregulating NPC cell cycle progression, and inhibiting radiation induced apoptosis XREF_BIBR, XREF_BIBR, XREF_BIBR."
27157611
reach
"Jab1 and CSN5 promotes NPC cell growth."
22867945
reach
"We also found that knockdown of CSN5 remarkably suppressed cell growth by inducing cell cycle arrest and apoptosis promotion in NSCLC cells."
29596838
reach
"Knockdown of COPS5 and COPS6 inhibited cell growth and migration of the CAL27 and SCC25 cell lines."
34630710