Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TGFBR1 activates SERPINE1. 3 / 3

| 3

➶

reach

"TGF-beta caused ALK5 mediated upregulation of PAI-1, Smad7, and fibronectin and in pericytes at lower TGF-beta concentrations than in endothelial cells."

19959647

➶

reach

"Moreover, transient transfection with Nrf2 decreased PAI-1 promoter activities stimulated by either TGF-beta treatment or ALK5 cotransfection in a dose dependent manner (XREF_FIG)."

23056222

➶

reach

"Indeed, lobeglitazone treatment successfully inhibited TGF-beta and ALK5 and Smad3, 4 stimulated PAI-1 promoter activity both in NRK-49F cells and RMCs (XREF_FIG)."

28256116

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

Other Services

This Service

This Project

IndraLab

Statements

TGFBR1 activates SERPINE1. 3 / 3

Our Sources:

Databases

Reading