IndraLab

Statements

Phosphorylated MTOR phosphorylates EIF4EBP1. 4 / 4
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sparser
"Phosphorylation of 4E-BP1 by p-mTOR releases 4E-BP1 from the mRNA cap-binding protein eIF4E, triggering the process of translation and protein synthesis [ xref , xref ]."
28005970
sparser
"In general, p-mTOR induces phosphorylation of 4E-BP1 and P70S6K, and initiation of translation and protein synthesis."
28005970
reach
"Given the quantitative downregulation of p-mTOR at Ser2448, this finding is sensible as p-mTOR phosphorylates 4EBP1 to allow eventual translation initiation."
28963127
reach
"In general, p-mTOR induces phosphorylation of 4E-BP1 and P70S6K, and initiation of translation and protein synthesis."
28005970