IndraLab

Statements


EGF binds EGFR and PDCD6IP. 3 / 3
| 3

sparser
"Moreover, Alix is known to be indirectly associate with EGFR and suppress its endocytosis ( xref ) and we observed that galectin-3 regulates the association of Alix and EGFR after EGF stimulation, as this association is diminished in the absence of galectin-3 ( xref )."

sparser
"These results further demonstrate that ALIX V mediates the EGF-induced ALIX interaction with activated and ubiquitinated EGFR."

sparser
"Thus direct recognition of ubiquitinated EGFR by the ALIX V domain is likely to be one of the major causes for EGF-induced ALIX interaction with EGFR."