IndraLab

Statements


EGFR binds GAB1 and GRB2. 2 / 2
| 2

sparser
"Gab1 interacts with EGFR via constitutively bound Grb2, becomes phosphorylated and binds PI3-K, resulting in its activation, consequently, enhancement of PIP3 level in the cell membrane."

sparser
"It is well established that Gab1 binds directly and specifically to Met , and strong evidence indicates that Gab1 binds EGFR indirectly via Grb2 , although direct binding has also been suggested ."