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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BRAF-V600K activates phosphorylated ERK. 2 / 2

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"Induction of the expression of BRAF V600E, V600K, K601E, L597Q, G469A, G469V, or G464V to levels comparable to those of endogenous BRAF caused significant induction of p-MEK and p-ERK and marked inhib[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Inductions of the expression of BRAF V600E, V600K, K601E, L597Q, G469A, G469V, or G464V at levels comparable to those of endogenous BRAF caused significant induction of p-MEK and p-ERK and marked inhibition of RAS-GTP and pCRAF S338."

26343582

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...