Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TGFB bound to its activates SMAD3. 3 / 3

| 3

➶

reach

"TGF-β binds to its cognate receptor TGF-β type II receptor, inducing the nuclear translocation of Smad2 and Smad3, which regulate the transcription of fibrotic target genes (Zhang et al., 2021a)."

34805276

➶

reach

"TGF-beta binding to its receptor triggers the activation of both Smad2 and Smad3."

24108699

➶

reach

"The binding of TGF-β to its receptors TGFR1 and TGFR2 activates Smad2 and Smad3 through direct phosphorylation."

31817513

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

Other Services

This Service

This Project

IndraLab

Statements

TGFB bound to its activates SMAD3. 3 / 3

Our Sources:

Databases

Reading