IndraLab

Statements


BRAF activates ELK1. 4 / 4
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"In addition, transfection of B-Raf greatly increased the activation of Elk-1 by RapV12 in untreated PC12 cells."

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"Expression of BRAF and HRAS induced the activation of ELK1 to a similar level."

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"Transfection of B-Raf into PC12 cells increased forskolin 's activation of Elk-1."

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"Inhibition of B-Raf with PLX4720 or of MEK with U0126 effectively inhibited 8-Br-cAMP-dependent Elk1 acti vation with respective IC 50 (median inhibitory concentration) values of 300 nM and 1 muM (XREF_FIG)."