Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Phosphorylated TSC2 inhibits RHEB. 1 / 1

| 1

➶

reach

"Phosphorylation of TSC2 by AKT results in the activation of mTORC1, as the phosphorylated TSC2 no longer inhibits the Ras homolog enriched in brain (Rheb) protein that is critically required for mTORC1 functions 40."

24222088

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...