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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MDM2 leads to the phosphorylation of TP53 phosphorylated on S20 on S20. 1 / 1

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reach

"ATM indirectly regulates MDM2 mediated degradation of p53 through phosphorylation of Chk2 which then phosphorylates p53 at Ser 20 to prevent the formation of the MDM2 and p53 complex."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...