IndraLab

Statements


TLE1 binds CTNNB1 and LEF1. 2 / 2
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"The observation that β-catenin and CK2 alternate with TLE1 for binding to the CycD1 gene was confirmed by real-time PCR ChIP ( Figure 1 C) and indicates that LEF-1 cannot bind simultaneously to β-cate[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"Since TLE1 binds antagonistically with β-catenin to DNA-bound Lef-1, decreasing affinity for TLE1 would also favor transcriptional activation."