IndraLab

Statements

NCAPD2 binds CTNNB1 and LEF1. 3 / 3
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"The results are consistent with the general pathway in which Lef-1 forms a bipartite transcriptional activation complex with β-catenin ( Behrens et al., 1996; Willert and Nusse, 1998 )."
12039047
sparser
"Overexpression or constitutive activation of ILK has been shown to result in an invasive phenotype concomitant with downregulation of E-cadherin expression, translocation of β-catenin to the nucleus, and formation of the LEF-1–β-catenin bipartite complex ( xref ; xref )."
11402061
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"We also show that complementary charged and hydrophobic amino acids are required for formation of the bipartite beta-catenin-LEF-1 transcription factor."
10966653