IndraLab

Statements


CTNNB1 bound to VDR inhibits CTNNB1. 2 / 2
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"The VDR has been proposed as a potential mediator that could modulate the effects of vitamin D. For example, VDR interacts with beta-catenin and inhibits beta-catenin signalling that is deregulated in most CRCs."

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"Interestingly, VDR and LXR can both directly bind to beta-catenin, thereby preventing beta-catenin from binding to its target sites."