Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53 bound to BCL2 activates apoptotic process. 2 / 2

| 2

➶

reach

"In the mitochondria, p53 directly interacts with Bcl-2 to block its anti-apoptotic activity and induces apoptosis by interacting with pro apoptotic proteins such as Bax."

33614633

➶

reach

"Taken together, these findings establish an interaction between p53, c-myc, Bcl-2, p21, p27 and PI3K and Akt pathway and CF induced apoptosis in MSTO-211 and HCT-116 cells, which may improve prevention outcomes for mesothelioma and colon cancer."

24598211

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...