IndraLab

Statements

CTNNB1 bound to LEF1 activates LEF1. 2 / 2

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"Of note, beta-catenin binds to Lef1 and activates Lef1 transcription complex, leading to down-regulation of E-cadherin expression [XREF_BIBR]."

33388549

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reach

"Similarly, the interaction between nuclear beta-catenin and TCF-4 or LEF-1 was reduced by CaSR activation, indicating an inhibitory association of beta-catenin and TCF-4 or LEF-1 in the nucleus."

27108064

INDRA sources:

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IndraLab

Statements

CTNNB1 bound to LEF1 activates LEF1. 2 / 2

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