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Modified miR-139-5p decreases the amount of IRS1. 1 / 1
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"In conclusion, our study confirmed that 1) elevated levels of miR-139-5p in the pancreatic tissues of diabetic rats can suppress IRS1 gene expression to promote cell apoptosis, and 2) liraglutide has anti-apoptotic effects by downregulating miR-139-5p levels and upregulating IRS1 gene expression."