IndraLab

Statements


MTOR decreases the amount of EIF4EBP1. 3 / 26
| 3

reach
"In the present study, in excellent agreement with the previous reports, metformin markedly activated AMPK and inactivated mTOR, thereby decreasing the levels of downstream effectors p-S6K1 and p-4EBP1 in MCF-7 and FSaII cells in vitro (XREF_FIG)."

reach
"Moreover, while transfection of mTOR WT significantly increased the gene and protein expression of p4EBP1 and Cyclin D1 in CNE-2 cells, mTOR siRNA significantly inhibited the gene and protein expressi[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Moreover, we found that transfection with mTOR WT significantly upregulated the mRNA expression of p4EBP1 and Cyclin D1, while mTOR siRNA transfection significantly inhibited the mRNA expression of p4[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"