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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

AKT1 inhibits RAF1. 4 / 6

3 | 1

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signor

"Akt and protein kinase a (pka) phosphorylate s259 on raf-1 and inhibit its activity."

16854453

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reach

"The modular map shows that the AKT1 module inhibits RAF1 and consequently MAPK1/3-module pathways."

26205660

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signor

"Akt and protein kinase a (pka) phosphorylate s259 on raf-1 and inhibit its activity."

10576741

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signor

"Akt negatively regulates the raf and gsk-3 kinases and the cell cycle regulatory transcription factor fkhr."

22798428

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

AKT1 inhibits RAF1. 4 / 6

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