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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BRAF-G466V activates ERK. 2 / 2

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"The BRAF mutants G466V, D594A, D594G, D594E, D594N, D594V and G596C did not induce MEK or ERK activation compared to wt-BRAF."

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"Y472C BRAF and G466V BRAF both activated MEK and ERK to levels at or above those observed after transfection with wt BRAF."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...