IndraLab

Statements


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"Both alphaE- and alphaN-catenin bind to beta-catenin with a Kd of 20 nM, and this affinity is increased by an order of magnitude when cadherin is bound to beta-catenin."

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"Thus, this NH 2 -terminal domain is essential for alphaN-catenin binding to beta-catenin."

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"At adhesion sites, beta-catenin and alphaN-catenin form a complex that is linked via alphaN-catenin to the actin cytoskeleton, thus providing a potential link between cadherins at the cell surface and the actin cytoskeleton within the leading processes of radially migrating neurons."

No evidence text available