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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

NGF bound to HCLS1 activates cell differentiation. 2 / 2

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"NGF, which can bind to endogenous p75, did not induce differentiation but enhanced the EGF induced response, leading to differentiation of almost all cells."

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"For example, while binding of NGF to TrkA receptors or to TrkA and p75 heteromers leads to cell survival and differentiation, binding of NGF to p75 leads to apoptosis in most cell types (Yan et al., 2[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...