IndraLab

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"As expected, signaling downstream of Cdc42 and Rac1 were impaired in the absence of Rasip1 or Arhgap29, as the active (phosphorylated) form of key GTPase effector kinases, such as pPak4, pSrc, pB-Raf, pC-Raf and pErk, were reduced in siRNA-depleted ECs ( xref and xref )."