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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ZUP1 activates nuclear factor kappa-light-chain-enhancer. 1 / 1

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"For instance, USP7, a host DUB, prevents degradation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) by deubiquitination from K48 of NF-κB p65 subunit in the TLR (TLR3 and TLR9) pathway to enhance stability of NF-kB, which upregulates the transcription of pro-inflammatory cytokines [29] ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...