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ZUP1 inhibits PINK1 Parkin-dependent mitophagy. 1 / 1
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eidos
"In addition , recent studies identified two DUBs that suppress PINK1 / Parkin-dependent mitophagy : USP33 , which acts by removing K6 - , K11 - , K48 - , and K63-linked ubiquitin conjugates on Parkin ; and USP36 , which acts by downregulating ATG14 [ 400,401 ] ."