IndraLab

Statements

TP53-R72P activates apoptotic process. 5 / 5
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"40 The Pro variant of p53 Arg72Pro is associated with reduced ability to induce apoptosis, 41 lower response rates, and worse outcomes in some cancers."
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"These findings support our result indicating that the p53 R72P triggered apoptosis pathway and the Arg72 allele may play an important role in the susceptibility of apoptosis in human mitochondrial dia[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We also examined the effect of TP53 Arg72Pro polymorphism on irradiation induced apoptosis (IA)."
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"Moreover, we have previously described that the human Tp53 Arg72Pro single nucleotide polymorphism (SNP) controls susceptibility to ischemia induced neuronal apoptosis and governs the functional outcome of patients after stroke."
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"The TP53 Arg72Pro polymorphism alters the ability of the TP53 protein to induce apoptosis versus cell-cycle arrest XREF_BIBR - XREF_BIBR."
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