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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

RHEB binds TSC2 and MTOR. 2 / 2

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"The gene product of PKD1 , polycystin-1, interacts with TSC2, which forms a complex with the GTP-binding protein RHEB upstream of mTOR."

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"We performed co-immunoprecipitations (co-IPs) to explore if the changes in TSC2 dynamics documented above, correlate with changes in the interaction of Rheb with TSC2 and mTOR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...