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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MDM2 bound to MDM4 increases the amount of ubiquitinated MDM2. 1 / 1

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"Compounds that disrupt the Mdm2-MdmX interaction will result in reduced E3 ligase activity of Mdm2 and MdmX complex consequently reducing the amounts of ubiquitinated Mdm2 and ubiquitinated MdmX and the FRET signals."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...