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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

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Nanoparticles decreases the amount of IRS1. 4 / 4

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"As shown in XREF_FIG, the expression level of IRS-1 was significantly reduced by miR-126 NPs compared with control dsRNA NPs."

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"On the other hand, miR-126 NPs reduced IRS-1 levels in rabbit SMCs and reduced the proliferation and migration of VSMCs via the suppression of IRS-1."

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"Thus, miR-126 NPs most likely reduced the levels of IRS-1 through its binding to the IRS-1 3 '-UTR."

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"We also confirmed that IRS-1 protein levels were reduced by the induction of miR-126 NPs compared with control NPs (XREF_FIG)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

Nanoparticles decreases the amount of IRS1. 4 / 4

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