IndraLab

Statements


EFNB1 binds EGFR and ERBB2. 8 / 8
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sparser
"The data suggest that EFNB1 associates with ERBB1 and ERBB2 (alone or in combination) and that PTPN13 modulates these interactions by regulating EFNB1 phosphorylation and downstream signaling."

sparser
"Our data suggest that PTPN13 modulates EFNB1-mediated signaling and that EFNB1 associates with ERBB1 and ERBB2."

reach
"Both of these BL breast cancer cell lines demonstrate over-expression of ErbB1 XREF_BIBR, XREF_BIBR suggesting that ErbB1 may hetero-dimerize with low levels of endogenous ErbB2 (forming an ErbB1, ErbB2, and EphrinB1 complex) and mediate signaling from the complex."

sparser
"Consistent with our previous studies, ERBB1 and ERBB2 associate with EFNB1 in both cell types ( xref )."

sparser
"Here we report that, like ERBB2, ERBB1 associates with EFNB1."

sparser
"EFNB1 associates with ERBB1 and ERBB2."

sparser
"Given that EFNB1 associates with ERBB1 and ERBB2, we wondered whether treatment with targeted drugs mediates changes in partner associations within these complexes that might account for sustained signaling in the presence of drug."

sparser
"These data show that ERBB1 and ERBB2 associate with EFNB1 in primary human tonsil cells as well as those expressing HPV oncogenes."