IndraLab

Statements


Modified CTNNB1 increases the amount of LEF1. 2 / 2
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"However, the co-expression of FLAP1, p300 and beta-catenin caused synergistic enhancement of LEF1 and TCF mediated transcription (bar 8)."

reach
"This increase in beta-catenin expression would be expected to interact with and increase TCF and LEF1 target gene expression in these cells, a pathway contributing to breast cancer progression."