A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.



phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

HBEGF binds EGF, EGFR, and AREG. 1 / 1
| 1
"Upon binding of EGFR ligands such as EGF, HBEGF, or amphiregulin (AREG), EGFR undergoes dimerization and autophosphorylation through its intrinsic tyrosine kinase activity and activates numerous signaling pathways including the protein kinase C (PKC) pathway and the p42/44 mitogen-activated protein kinase (MAPK) pathway [ xref , xref , xref , xref ]."