IndraLab
Statements
sparser
"Upon binding of EGFR ligands such as EGF, HBEGF, or amphiregulin (AREG), EGFR undergoes dimerization and autophosphorylation through its intrinsic tyrosine kinase activity and activates numerous signaling pathways including the protein kinase C (PKC) pathway and the p42/44 mitogen-activated protein kinase (MAPK) pathway [ xref , xref , xref , xref ]."