IndraLab

Statements


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"Notum overexpression was associated with intracellular β-catenin localization (100% of cases) and also observed in early lesions."

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"High levels of NOTUM protein were significantly associated with intracellular (nuclear or cytoplasmic) accumulation of beta-catenin protein: all 10 HCC with high intracellular beta-catenin also had high NOTUM expression, whereas only 2 of 30 cases (6.7%) without intracellular beta-catenin had high NOTUM expression (P < 0.00001)."