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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CDC42 activates KRAS. 2 / 2

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"Our data showed that Cdc42 knockdown remarkably inhibited KRAS activated MDCK cell growth at low cell density but the cell growth was significantly enhanced after reaching 100% confluence."

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"On the contrary, in MEF cells which did not form tight junction, Cdc42 deletion abrogated the promotive effect of KRAS upon cell proliferation."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...