IndraLab

Statements


MDM2 bound to region activates TP53. 1 / 1
| 1

reach
"In the absence of DNA damage, MDM2 binds to the N-terminal region of p53 and inhibits its activity by blocking p53 mediated transactivation, exporting p53 from the nucleus to the cytoplasm, and promoting the proteasomal degradation of p53."