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CTNNB1 bound to TRIM33 inhibits CTNNB1. 1 / 1

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"Our novel findings demonstrate that prolonged Wnt stimulation can lead to activation of PKCdelta; then, phosphorylation of beta-catenin at Ser715 by activated PKCdelta facilitates the interaction between TRIM33 and beta-catenin, which induce beta-catenin degradation and hence shut down Wnt signaling."

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IndraLab

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CTNNB1 bound to TRIM33 inhibits CTNNB1. 1 / 1

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