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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CTNNB1 bound to PAK1 activates CTNNB1. 1 / 1

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"PAK1 also interacts with beta-catenin to promote beta-catenin and TCF4 activation in gastric epithelial cells and it phosphorylates beta-catenin at Serine 675, which increases the stability and transcriptional activity of beta-catenin in colon cancer cells XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...