IndraLab

Statements

EGF leads to the phosphorylation of EGFR on Y1172. 7 / 7
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bel
"Table 4. Quantification data from MRM-QTRAP analyses. Also see fig 4a. 2-fold cutoff; 32 min timepoint FC/ 0 min timepoint FC"
17389395
reach
"EGF also rapidly increased EGFR (Tyr 1148) and ERK1/2 phosphorylation (Thr-202 and Tyr-204), and both of these effects were enhanced by miR-10b (XREF_FIG)."
24096486
sparser
"Hence, this observation indicated an inhibitory effect of NDRG1 on EGF-induced EGFR phosphorylation at Tyr1148, which is important for stimulating c-Src activation [ xref ]."
25860930
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"
17081983
bel
"TABLE V Survey of cell signaling proteins that show a reaction to EGF ligand stimulation over a 180-min time course - 500ng/mL EGF results"
18687633
bel
"Purified EGFR was phosphorylated in vitro with EGF in the presence of various synthetic peptides."
16402038
bel
"To address this problem, we use quantitative mass spectrometry to analyze dynamic effects of HER2 overexpression on phosphotyrosine signaling in human mammary epithelial cells stimulated by epidermal growth factor (EGF) or heregulin (HRG). [This is from the 'Suplementary Table with Full Data Set\" (http://www.nature.com/msb/journal/v2/n1/suppinfo/msb4100094_S1.html). The cutoff used was a 2.5 fold or greater increase at any of the 5, 10 or 30 minute time points.]"
17016520