Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BDNF bound to TrkB receptors activates ERK. 2 / 2

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"The binding of BDNF to TrkB receptors and/or modulation of NMDA receptors activates AKT, ERK1/2 or PKC; the main activators of the mTOR signaling (Hoeffer and Klann, 2010; Numakawa et al., 2014; Chang[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"XREF_BIBR BDNF bound TrkB receptors to trigger PI3K and Akt and mitogen activated protein kinase and extracellular signal regulated kinase pathways."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...