IndraLab

Statements

TPX2 leads to the phosphorylation of TACC3. 2 / 2
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"We reasoned that during oocyte meiotic maturation, in the absence of centrosomes, TPX2 could indirectly induce the phosphorylation and activation of TACC3 at MTOCs."
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"We reasoned that during oocyte meiotic maturation, in the absence of centrosomes, TPX2 could indirectly induce the phosphorylation and activation of TACC3 at MTOCs."
18833336
TPX2 phosphorylates TACC3-F543A. 1 / 1
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"By contrast, TACC3 F543A can be phosphorylated by TPX2 activated Aurora-A and supports MT assembly via the ch-TOG polymerase, but it can not locally activate Aurora-A, which results in reduced S574 phosphorylation and weak complexation with clathrin."
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