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MAP2K1 phosphorylates MAPK1. 10 / 131
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reach
"For example, MEK1 and MEK2 phosphorylate ERK1 and ERK2 in the cellular * Corresponding author."

reach
"Note that MEK1 fully phosphorylated MAPK and Erk2 by 2 h. PKG and MAPK placed approximately one molecule phosphate onto each molecule of preferred substrate, CK II was somewhat less efficient, incorpo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"In the second model arrestin can act as a true scaffold, bringing both MEK1 and ERK2 into close proximity to each other, thereby facilitating the phosphorylation of ERK2 by MEK1."

reach
"Raf-1 then activates MEK1, which phosphorylates ERK1 and ERK2."

sparser
"MAPK signaling is enhanced by receptor tyrosine kinases, integrins, and G-protein coupled receptors; MAP2K1 phosphorylates ERK1 and ERK2 [ xref ]."

sparser
"Next, we tested whether arrestin binding affects ERK2 phosphorylation by MEK1."

reach
"Mek1 and Mek2 mediate the phosphorylation of Erk1 and Erk2, which also form dimers XREF_BIBR."

sparser
"Within the cascade, the doubly phosphorylated MEK1 phosphorylates the extracellular-signal-regulated kinases ERK1 and ERK2 ( xref )."

rlimsp
"Expression of wild-type LC-PTP in 293T cells suppressed the phosphorylation of ERK2 by a mutant MEK1, which was constitutively active regardless of upstream activation signals. No suppression of the phosphorylation was observed by LC-PTPCS, a catalytically inactive mutant."

sparser
"We here show that the MEK1-dependent phosphorylation of ERK2 is involved in NTHi-induced CXCL2 up-regulation in the SLFs."