IndraLab

Statements

PPP2CA dephosphorylates AKT1 on S473. 5 / 5
2 3 |
signor
"Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes"
15367694
hprd
No evidence text available
12637511
signor
"Overexpression of BTBD10 increased phosphorylation levels of Akts at both Thr(308) and Ser(473) while the reduction of the endogenous BTBD10 level resulted in a decrease in the phosphorylation levels of Akts. In vitro analysis indicated that BTBD10 bound to protein phosphatase 2A (PP2A) and inhibited dephosphorylation of Akts by PP2A."
18160256
hprd
No evidence text available
12637511
hprd
No evidence text available
12637511
PPP2CA dephosphorylates AKT1 on T308. 5 / 5
2 3 |
hprd
No evidence text available
12637511
signor
"Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes"
15367694
hprd
No evidence text available
12637511
hprd
No evidence text available
12637511
signor
"Overexpression of BTBD10 increased phosphorylation levels of Akts at both Thr(308) and Ser(473) while the reduction of the endogenous BTBD10 level resulted in a decrease in the phosphorylation levels of Akts. In vitro analysis indicated that BTBD10 bound to protein phosphatase 2A (PP2A) and inhibited dephosphorylation of Akts by PP2A."
18160256
PPP2CA leads to the dephosphorylation of AKT1. 2 / 2
| 1 1
sparser
"It was also reported that the Akt pathway is down-regulated by C2-ceramide in the NGF-treated PC12 cells as a result of enhanced dephosphorylation of Akt1 by protein phosphatase (CAPP-PP2A) [ xref ]."
24420784
reach
"Suppression of PPP2CA enhanced (p < 0.05) VEGF induced AKT1, but not ERK1/2 phosphorylation, whereas inhibited (p < 0.05) FGF2 induced ERK1/2 and p38 MAPK and slightly attenuated FGF2 induced AKT1 phosphorylation."
19692121
PPP2CA dephosphorylates AKT1 on T450. 1 / 1
1 |
signor
"Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2a and dephosphorylation of akt and glycogen synthase kinase 3 beta"
11839802